Preheat oven to 400 F.
Mix the garlic powder, salt, pepper, melted butter, and hot sauce in a small bowl.
Add the cauliflower to a large bag.
Add prepared sauce in the bag and shake it until the cauliflower florets are fully coated.
Spread cauliflower on baking sheet and bake it for 20 minutes at 400 F.
Serve in the bowl.